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Drug ReportsCalcium dobesilate
Calcium dobesilate
Calcium dobesilate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Financial
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Events Timeline
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3M
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2Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Completion date
Results first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name
Status
Last Update
e l f camo semi matte cc spf 30 light 205 nC2002632024-02-06
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C05: Vasoprotectives
— C05B: Antivaricose therapy drugs
— C05BX: Other sclerosing agents in atc
— C05BX01: Calcium dobesilate
— C05BX51: Calcium dobesilate, combinations
HCPCS
No data
Clinical
Clinical Trials
1332 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Multiple myelomaD009101—C90.01001845845295
Macular edemaD008269——42118252993
Precursor cell lymphoblastic leukemia-lymphomaD054198—C91.02844211486
Postoperative painD010149—G89.18261120843
Postoperative nausea and vomitingD020250EFO_0004888—17819538
VomitingD014839HP_0002013R11.1—5164934
CataractD002386HP_0000518H26.9—21013833
Retinal vein occlusionD012170EFO_1001157H34.8122571529
NeoplasmsD009369—C8081053326
Non-hodgkin lymphomaD008228—C85.9810—1—18
Show 131 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LeukemiaD007938—C953158—326
LymphomaD008223—C85.97144—123
Immunoglobulin light-chain amyloidosisD000075363——882——15
Mantle-cell lymphomaD020522—C83.13121——14
Waldenstrom macroglobulinemiaD008258HP_0005508C88.03101——13
Hodgkin diseaseD006689—C81452——11
Philadelphia chromosomeD010677——162——8
Myelodysplastic syndromesD009190—D46431—17
Myeloid leukemia acuteD015470—C92.0531——7
Brain neoplasmsD001932EFO_0003833C71233——7
Show 71 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AmyloidosisD000686EFO_1001875E8567——210
Plasma cell neoplasmsD054219——24——16
Follicular lymphomaD008224—C8225———6
Ovarian neoplasmsD010051EFO_0003893C5621——24
Plasma cell leukemiaD007952—C90.112——14
Biphenotypic leukemia acuteD015456—C95.0—4———4
PlasmacytomaD010954—C90.322———4
B-cell chronic lymphocytic leukemiaD015451—C91.114———4
Smoldering multiple myelomaD000075122———4———4
Large-cell lymphoma anaplasticD017728—C84.613———4
Show 65 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———8———19
GlioblastomaD005909EFO_0000515—2———24
Cesarean sectionD002585——1———23
PruritusD011537HP_0000989L292———13
Hairy cell leukemiaD007943—C91.42————2
Pituitary neoplasmsD010911——1———12
AstrocytomaD001254EFO_0000271—2————2
OligodendrogliomaD009837EFO_0000631—2————2
T-cell lymphomaD016399——2————2
MesotheliomaD008654—C452————2
Show 39 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SarcomaD012509——————22
Respiratory soundsD012135HP_0010307R06.1————22
Deglutition disordersD003680HP_0002015R13.1————22
TrismusD014313——————22
MyopiaD009216EFO_0003927H52.1————22
AstigmatismD001251EFO_0004222H52.2————22
PregnancyD011247EFO_0002950Z33.1————22
Brenner tumorD001948——————11
Endometrioid carcinomaD018269——————11
Fallopian tube neoplasmsD005185——————11
Show 58 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCalcium dobesilate
INNcalcium dobesilate
Description
Calcium dobesilate is a vasoprotective. It is the calcium salt of dobesilic acid. It is a synthetic molecule with the ability to reduce capillary permeability in the body. In Switzerland the drug is sold by the pharmaceutical company OM Pharma under the trade name of Doxium in capsules containing 500 mg of active ingredient.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
O=S(=O)([O-])c1cc(O)ccc1O.O=S(=O)([O-])c1cc(O)ccc1O.[Ca+2]
Identifiers
PDB—
CAS-ID117552-78-0
RxCUI—
ChEMBL IDCHEMBL2106191
ChEBI ID—
PubChem CID29963
DrugBankDBSALT002519
UNII ID5921X1560Q (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 921 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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64 adverse events reported
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